STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0573Conserved hypothetical protein. (220 aa)    
Predicted Functional Partners:
PAE0317
GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid.
  
  
 0.820
trpC
Indole-3-glycerol-phosphate synthase; Amino acid biosynthesis; Aromatic amino acid family; Belongs to the TrpC family.
       0.574
PAE0568
Cation efflux system protein, conjectural; Transport and binding proteins; Cations.
       0.573
queC
Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.508
PAE0329
Conserved hypothetical protein.
  
    0.458
PAE1328
Conserved hypothetical protein.
 
    0.458
PAE2137
Hypothetical protein.
     
 0.452
PAE3547
Heat shock protein, htpX homolog, conjectural; Cellular processes; Adaptations to atypical conditions.
 
     0.447
queE
Coenzyme PQQ synthesis protein, conjectural; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
     
 0.435
PAE0983
Conserved hypothetical protein.
 
     0.428
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.