STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0616Biosynthesis of cofactors, prosthetic groups, and carriers; Other. (346 aa)    
Predicted Functional Partners:
PAE0617
Oxidoreductase, truncation; Unclassified.
       0.799
ilvD
Dihydroxy-acid dehydratase (ilvD); Amino acid biosynthesis; Pyruvate family; Belongs to the IlvD/Edd family.
       0.684
PAE2109
DNA-directed DNA polymerase (B3); DNA metabolism; DNA replication, recombination, and repair.
   
    0.620
PAE1113
Possible DNA-directed DNA polymerase (B2); DNA metabolism; DNA replication, recombination, and repair.
   
    0.529
PAE2180
DNA-directed DNA polymerase (B1); DNA metabolism; DNA replication, recombination, and repair.
   
    0.529
PAE3088
Oligopeptide binding protein, putative; Transport and binding proteins; Amino acids, peptides and amines.
     
 0.496
PAE2243
Conserved hypothetical protein.
     
 0.492
PAE0620
Hypothetical protein.
       0.490
paudg
Uracil DNA glycosylase (Pa-UDGa); Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA. Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.
      
 0.482
PAE0653
Conserved hypothetical protein.
      
 0.482
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.