STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0692Hypothetical protein with partial (eukaryotic) protein kinase domain; Unclassified. (75 aa)    
Predicted Functional Partners:
PAE3333
Conserved hypothetical protein.
   
 0.894
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
   
 0.893
PAE1536
Conserved protein (possible dual specificity phosphatase); Unclassified.
   
 0.870
PAE2004
Serine/threonine specific protein phosphatase; Regulatory functions; General.
   
 0.849
PAE0696
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
   
 0.832
PAE3171
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
   
 0.832
PAE2926
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
   
  0.731
PAE0556
Amino acid permease; Transport and binding proteins; Amino acids, peptides and amines.
    
 0.725
ndk
Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
    
 
 0.717
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
   
 
 0.709
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.