Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PAE0712Surface layer-associated STABLE protease, conjectural; Protein fate; Degradation of proteins, peptides, and glycopeptides; Belongs to the peptidase S8 family. (1258 aa)    
Predicted Functional Partners:
PAE0653
Conserved hypothetical protein.
  
     0.636
PAE3657
Transport and binding proteins; Unknown substrate.
 
     0.612
PAE1049
Hypothetical protein.
  
  
 0.597
pth
Conserved hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.569
PAE2935
Conserved hypothetical protein.
  
     0.563
PAE0061
Extracellular solute binding protein, conjectural; Transport and binding proteins; Anions.
 
     0.554
PAE3030
Oligosaccharyl transferase STT3 homolog; Protein fate; Protein modification and repair.
 
  
 0.549
PAE0708
Hypothetical protein.
       0.508
PAE0055
Hypothetical protein.
 
    0.490
PAE3333
Conserved hypothetical protein.
 
 
 0.463
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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