Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE0715Hypothetical protein. (200 aa)    
Predicted Functional Partners:
PAE0714
Diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (mutT/nudix family protein); DNA metabolism; DNA replication, recombination, and repair.
       0.679
PAE0716
Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle.
       0.564
PAE0717
Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle.
       0.564
PAE0718
Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle.
       0.562
PAE0719
Succinate dehydrogenase subunit D (sdhD); Energy metabolism; TCA cycle.
       0.560
PAE3570
Sulfate ABC transporter, permease protein, putative; Transport and binding proteins; Anions.
  
    0.468
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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