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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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[Homology]
Score
PAE0719Succinate dehydrogenase subunit D (sdhD); Energy metabolism; TCA cycle. (118 aa)    
Predicted Functional Partners:
PAE0718
Succinate dehydrogenase cytochrome b subunit (sdhC); Energy metabolism; TCA cycle.
  
 0.999
PAE0716
Succinate dehydrogenase flavoprotein subunit (sdhA); Energy metabolism; TCA cycle.
  
 0.998
PAE0717
Succinate dehydrogenase iron-sulfur subunit (sdhB); Energy metabolism; TCA cycle.
  
 0.998
sucC
succinyl-CoA synthetase beta subunit (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.990
PAE2132
Fumarate hydratase class I alpha subunit; Energy metabolism; TCA cycle.
  
 
 0.961
sucD
succinyl-CoA synthetase alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.959
PAE2131
Fumarate hydratase class I beta subunit; Energy metabolism; TCA cycle.
  
 
 0.958
PAE2690
Iron-sulfur protein, putative; Energy metabolism; Electron transport.
  
 
 0.956
PAE2743
Fumarate hydratase class II; Energy metabolism; TCA cycle.
  
 
 0.930
PAE2563
Adenylylsulfate reductase alpha subunit part 1, authentic frameshift; Central intermediary metabolism; Sulfur metabolism.
  
 
 0.920
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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