Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE0725Electron transfer flavoprotein-quinone oxidoreductase; Energy metabolism; Electron transport. (424 aa)    
Predicted Functional Partners:
PAE0723
Ferredoxin like protein; Energy metabolism; Electron transport.
 
 
 0.992
PAE0722
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
 
 
 0.969
PAE0721
Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport.
 
 
 0.962
PAE3586
Electron transfer flavoprotein beta subunit (etfB); Energy metabolism; Electron transport.
  
 
 0.618
PAE3587
Electron transfer flavoprotein alpha subunit (etfA); Energy metabolism; Electron transport.
 
 
 0.589
pcn2
Proliferating-cell nuclear antigen homolog (PCNA); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
     
 0.557
PAE2159
Conserved hypothetical protein.
  
   
 0.516
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
       0.505
PAE2375
4-hydroxybenzoate octaprenyltransferase (ubiA); Biosynthesis of cofactors, prosthetic groups, and carriers; Menaquinone and ubiquinone.
 
  
 0.446
PAE1784
Conserved hypothetical protein.
  
  
 0.400
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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