Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE0771N-acyltransferase; Protein fate; Protein modification and repair. (176 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase catalytic subunit (pyrB); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis.
       0.792
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
   
 
 0.707
PAE1204
Pantothenate metabolism flavoprotein (dfp); DNA metabolism; DNA replication, recombination, and repair.
 
     0.702
PAE0772
Hypothetical protein.
       0.646
PAE0773
Conserved protein (possible type II secretion, gsp); Unclassified.
       0.646
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 
 0.625
PAE0768
Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis.
  
    0.620
rpl23
Ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
   0.615
PAE2352
RNase L inhibitor homolog; Unclassified.
  
    0.562
rpl18
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
   0.541
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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