node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAE0317 | PAE3165 | PAE0317 | PAE3165 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | GTP binding protein, putative; Unclassified. | 0.432 |
PAE0317 | guaA | PAE0317 | PAE3369 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.815 |
PAE0317 | queC | PAE0317 | PAE2074 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.864 |
PAE0317 | queE | PAE0317 | PAE0010 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | Coenzyme PQQ synthesis protein, conjectural; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.950 |
PAE0317 | tgtA | PAE0317 | PAE0777 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.610 |
PAE0776 | tgtA | PAE0776 | PAE0777 | Hypothetical protein. | Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.691 |
PAE3165 | PAE0317 | PAE3165 | PAE0317 | GTP binding protein, putative; Unclassified. | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | 0.432 |
PAE3165 | flpA | PAE3165 | PAE3228 | GTP binding protein, putative; Unclassified. | Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.453 |
PAE3165 | guaA | PAE3165 | PAE3369 | GTP binding protein, putative; Unclassified. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.939 |
PAE3165 | hisS | PAE3165 | PAE1553 | GTP binding protein, putative; Unclassified. | histidyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.650 |
PAE3165 | nusA | PAE3165 | PAE0669 | GTP binding protein, putative; Unclassified. | Transcription termination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family. | 0.560 |
PAE3165 | tgtA | PAE3165 | PAE0777 | GTP binding protein, putative; Unclassified. | Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.591 |
PAE3165 | truB | PAE3165 | PAE0865 | GTP binding protein, putative; Unclassified. | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.594 |
flpA | PAE3165 | PAE3228 | PAE3165 | Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | GTP binding protein, putative; Unclassified. | 0.453 |
flpA | guaA | PAE3228 | PAE3369 | Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.511 |
flpA | hisS | PAE3228 | PAE1553 | Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | histidyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.479 |
flpA | tgtA | PAE3228 | PAE0777 | Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.623 |
flpA | truB | PAE3228 | PAE0865 | Fibrillarin-like pre-rRNA processing protein (flpA); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.836 |
guaA | PAE0317 | PAE3369 | PAE0317 | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | 0.815 |
guaA | PAE3165 | PAE3369 | PAE3165 | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | GTP binding protein, putative; Unclassified. | 0.939 |