Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE0793Conserved protein (possible ATP binding); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (307 aa)    
Predicted Functional Partners:
PAE2926
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
    
 0.833
PAE1580
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
 
 0.808
PAE0791
Conserved hypothetical protein.
       0.762
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.746
PAE2928
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport; Belongs to the complex I 20 kDa subunit family.
     
 0.716
PAE2972
Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
       0.646
PAE1186
Conserved hypothetical protein.
       0.645
PAE2939
Conserved hypothetical protein.
 
  
 0.619
PAE3371
Gamma-glutamyltransferase; Biosynthesis of cofactors, prosthetic groups, and carriers; Glutathione.
   
 
 0.612
PAE0617
Oxidoreductase, truncation; Unclassified.
    
 0.597
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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