Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE0815Serine/threonine protein kinase, putative; Regulatory functions; General. (369 aa)    
Predicted Functional Partners:
PAE3333
Conserved hypothetical protein.
   
 0.894
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
   
 0.893
PAE2004
Serine/threonine specific protein phosphatase; Regulatory functions; General.
 
 
 0.883
PAE1536
Conserved protein (possible dual specificity phosphatase); Unclassified.
   
 0.870
PAE0816
Conserved protein with Forkhead-associated (FHA) domain; Unclassified.
 
 
 
 0.858
PAE0696
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
   
 0.832
PAE3171
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
   
 0.832
PAE2981
Acetylpolyamine aminohydrolase, putative; Energy metabolism; Amino acids and amines.
  
 
 0.763
PAE2926
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
   
  0.731
PAE0556
Amino acid permease; Transport and binding proteins; Amino acids, peptides and amines.
    
 0.725
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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