Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0830Conserved hypothetical protein. (197 aa)    
Predicted Functional Partners:
PAE0831
Hypothetical protein.
       0.882
PAE0832
Adenylate cyclase; Purines, pyrimidines, nucleosides, and nucleotides; Purine ribonucleotide biosynthesis.
 
     0.805
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
  
    0.708
PAE0818
Conserved hypothetical protein; Belongs to the MEMO1 family.
 
    0.678
PAE0829
Hypothetical protein.
       0.609
PAE0827
Hypothetical protein.
       0.510
PAE2270
Small heat shock protein, hsp20 homolog, conjectural; Cellular processes; Adaptations to atypical conditions; Belongs to the small heat shock protein (HSP20) family.
 
    0.506
PAE3644
Hypothetical protein.
  
     0.489
PAE1349
Rieske iron sulfur protein (parR); Energy metabolism; Electron transport.
 
    0.481
PAE1636
Conserved hypothetical protein.
  
     0.474
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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