Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE0836Conserved hypothetical protein. (113 aa)    
Predicted Functional Partners:
PAE0837
Sugar-phosphate nucleotidyl transferase; Unclassified.
       0.879
PAE0835
Sugar kinase, possible phosphofructokinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the carbohydrate kinase PfkB family.
       0.781
PAE0838
Hypothetical protein.
       0.749
PAE0839
Hypothetical protein.
       0.749
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
       0.652
PAE2268
Protein synthesis; tRNA and rRNA base modification.
       0.603
PAE0834
Hypothetical protein.
       0.570
PAE2266
glycyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation.
       0.570
PAE3187
Conserved hypothetical protein.
       0.464
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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