Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0875Competence damage protein, conjectural; DNA metabolism; DNA replication, recombination, and repair; Belongs to the CinA family. (266 aa)    
Predicted Functional Partners:
PAE0876
Conserved hypothetical protein.
       0.788
PAE2176
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); Fatty acid and phospholipid metabolism; Biosynthesis; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.705
PAE1995
3-isopropylmalate dehydrogenase (leuB); Amino acid biosynthesis; Pyruvate family.
      0.653
PAE0877
Antioxidant protein, putative; Cellular processes; Toxin production and resistance.
       0.587
PAE0878
Hypothetical protein.
       0.559
PAE2055
Conserved hypothetical protein.
 
   
 0.547
PAE3326
Conserved hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
   
 0.492
PAE1012
Conserved hypothetical protein.
       0.470
PAE2990
Conserved hypothetical protein.
  
  
 0.410
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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