STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0879Conserved hypothetical protein. (129 aa)    
Predicted Functional Partners:
PAE0880
DNA-(apurinic or apyrimidinic site) lyase (endonuclease III, PaNth); DNA metabolism; DNA replication, recombination, and repair.
       0.642
PAE3573
Conserved hypothetical protein.
  
     0.613
thiI
Thiamine biosynthesis protein (thiI), probable; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.529
PAE1270
Conserved hypothetical protein.
  
     0.504
PAE2711a
Conserved hypothetical protein.
 
   
 0.497
PAE1287
Malate synthase (glcB); Central intermediary metabolism; Other.
  
     0.477
PAE2503
Conserved hypothetical protein, frameshift.
  
     0.475
PAE0882
Conserved hypothetical protein.
       0.471
PAE1543
Conserved hypothetical protein.
  
     0.465
PAE2449
Conserved hypothetical protein.
  
     0.457
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.