close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0920paREP15, putative coiled-coil protein. (191 aa)    
Predicted Functional Partners:
PAE0918
Histidinol-phosphate aminotransferase (hisC); Amino acid biosynthesis; Histidine family.
       0.752
PAE0922
Conserved hypothetical protein.
 
     0.718
PAE0355
Conserved hypothetical protein.
 
     0.620
PAE1883
Conserved hypothetical protein.
 
     0.613
PAE0926
Conserved hypothetical protein.
 
     0.553
PAE0923
Hypothetical protein.
       0.467
PAE0924
Conserved hypothetical protein.
       0.467
PAE0925
Hypothetical protein.
       0.467
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (38%) [HD]