STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0952Conserved hypothetical protein; Belongs to the UPF0215 family. (187 aa)    
Predicted Functional Partners:
PAE0953
Putrescine/spermidine binding protein, conjectural; Transport and binding proteins; Amino acids, peptides and amines.
       0.778
PAE0951
Aminotransferase, conjectural; Unclassified.
       0.763
PAE0737
Cell division control protein 6 (cdc6), putative; Involved in regulation of DNA replication.
 
     0.578
csl4
Conserved protein (RNA polymerase related); Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
 
     0.578
PAE1438
Cytidylyltransferase; Unclassified.
  
     0.571
PAE0949
Hydrogenase expression/formation protein HypE; Protein fate; Protein modification and repair.
       0.559
tiaS
Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.554
PAE2220
Conserved hypothetical protein.
 
     0.528
PAE2259
Conserved protein (possible cytidylyltransferase); Unclassified.
  
     0.524
ribK
Conserved hypothetical protein; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.509
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.