STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0953Putrescine/spermidine binding protein, conjectural; Transport and binding proteins; Amino acids, peptides and amines. (384 aa)    
Predicted Functional Partners:
PAE2893
Transport and binding proteins; Amino acids, peptides and amines.
 
 0.999
PAE2891
Transport and binding proteins; Amino acids, peptides and amines.
 
 
 0.998
PAE2890
Transport and binding proteins; Amino acids, peptides and amines.
 
  
 0.893
PAE0952
Conserved hypothetical protein; Belongs to the UPF0215 family.
       0.780
PAE0951
Aminotransferase, conjectural; Unclassified.
       0.762
PAE0949
Hydrogenase expression/formation protein HypE; Protein fate; Protein modification and repair.
       0.552
PAE3208
Helix-turn-helix protein; Unclassified.
 
   
 0.548
PAE2260
Agmatinase (speB); Central intermediary metabolism; Polyamine biosynthesis; Belongs to the arginase family.
 
   
 0.506
thiI
Thiamine biosynthesis protein (thiI), probable; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.475
PAE2993
DNA topoisomerase (topA); DNA metabolism; DNA replication, recombination, and repair.
     
 0.472
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.