STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1000P. aerophilum family 3 protein; Hypothetical; Conserved within genome. (176 aa)    
Predicted Functional Partners:
PAE0999
P. aerophilum family 59 protein; Hypothetical; Conserved within genome.
       0.773
PAE1001
Hypothetical; Conserved within genome.
       0.483
rtcB
Conserved hypothetical protein; GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair (By similarity). Joins RNA with 2',3'- cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends (By similarity); Belongs to the RtcB family.
       0.461
PAE1002
Acylamino-acid-releasing enzyme, conjectural; Protein fate; Protein modification and repair.
       0.435
gatD
Asparaginase (asnA); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.435
PAE1004
Conserved hypothetical protein.
       0.435
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.