STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1002Acylamino-acid-releasing enzyme, conjectural; Protein fate; Protein modification and repair. (627 aa)    
Predicted Functional Partners:
gatD
Asparaginase (asnA); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
 
 
   0.836
PAE3237
Beta-lactamase-like protein; Cellular processes; Toxin production and resistance.
 
     0.802
PAE1004
Conserved hypothetical protein.
       0.773
PAE1001
Hypothetical; Conserved within genome.
       0.686
PAE0264
Signal peptidase; Protein fate; Protein and peptide secretion and trafficking.
  
 
 0.599
PAE0999
P. aerophilum family 59 protein; Hypothetical; Conserved within genome.
       0.435
PAE1000
P. aerophilum family 3 protein; Hypothetical; Conserved within genome.
       0.435
PAE1302
Tricorn protease; Degrades oligopeptides; Belongs to the peptidase S41B family.
  
   
 0.409
PAE0885
Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
  
    0.400
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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