Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1004Conserved hypothetical protein. (176 aa)    
Predicted Functional Partners:
gatD
Asparaginase (asnA); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
  
    0.808
PAE1002
Acylamino-acid-releasing enzyme, conjectural; Protein fate; Protein modification and repair.
       0.773
PAE1001
Hypothetical; Conserved within genome.
       0.704
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
    0.679
PAE0261
Methylase, conjectural; Unclassified.
   
    0.558
PAE2210
Conserved hypothetical protein.
  
     0.437
PAE0999
P. aerophilum family 59 protein; Hypothetical; Conserved within genome.
       0.435
PAE1000
P. aerophilum family 3 protein; Hypothetical; Conserved within genome.
       0.435
PAE2071
Phosphoribosyl transferase; Unclassified.
 
    0.427
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
    0.411
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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