Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE1038D-3-phosphoglycerate dehydrogenase (serA); Amino acid biosynthesis; Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)    
Predicted Functional Partners:
PAE1309
Conserved hypothetical protein.
 
 0.948
PAE1284
Glycolate oxidase subunit glcE; Central intermediary metabolism; Other.
   
 0.928
PAE1286
Glycolate oxidase subunit glcD; Central intermediary metabolism; Other.
   
 0.928
PAE2035
D-lactate dehydrogenase; Energy metabolism; Fermentation.
   
 0.928
PAE1287
Malate synthase (glcB); Central intermediary metabolism; Other.
  
 
 0.924
PAE3068
Phosphoglycolate phosphatase (pgp), conjectural; Energy metabolism; Sugars.
 
  
 0.924
PAE1872
Isocitrate lyase; Central intermediary metabolism; Other.
  
 
 0.920
PAE1145
Conserved protein (3-hydroxyisobutyrate dehydrogenase family); Unclassified.
    
 0.919
PAE3495
Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.918
PAE2315
Unclassified.
  
 
  0.913
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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