STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1049Hypothetical protein. (403 aa)    
Predicted Functional Partners:
PAE1048
Hypothetical protein.
       0.732
PAE2662
Formate dehydrogenase alpha subunit; Energy metabolism; Electron transport.
 
   
 0.634
PAE0712
Surface layer-associated STABLE protease, conjectural; Protein fate; Degradation of proteins, peptides, and glycopeptides; Belongs to the peptidase S8 family.
  
  
 0.604
PAE2861
Molybdopterin oxidoreductase, membrane subunit; Energy metabolism; Electron transport.
 
     0.595
PAE1982
Aerolysin, part 1, authentic frameshift; Protein fate; Degradation of proteins, peptides, and glycopeptides.
  
  
 0.579
PAE3547
Heat shock protein, htpX homolog, conjectural; Cellular processes; Adaptations to atypical conditions.
 
 
 
 0.544
PAE2506
paREP11.
 
     0.529
PAE1173
Conserved hypothetical protein.
 
     0.523
PAE1051
Cysteine synthase; Amino acid biosynthesis; Serine family.
 
   
 0.522
ppcA
Conserved hypothetical protein; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
 
     0.511
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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