Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1058Glycerophosphoryl diester phosphodiesterase; Fatty acid and phospholipid metabolism; Degradation. (229 aa)    
Predicted Functional Partners:
PAE2176
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA); Fatty acid and phospholipid metabolism; Biosynthesis; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.794
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.784
PAE1056
thiF/moeB/hesA family protein; Unclassified.
  
 
 0.635
PAE1395
Phosphate ABC transporter, permease protein; Transport and binding proteins; Anions.
  
  
 0.599
PAE1226
DNA endonuclease, conjectural; DNA metabolism; DNA replication, recombination, and repair.
  
  
 0.489
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
  
 
 0.483
PAE2464
ABC transporter ATP-binding component; Transport and binding proteins; Amino acids, peptides and amines.
  
 
 0.477
PAE2480
Aldehyde dehydrogenase; Unclassified.
  
 
 0.457
PAE1386
Phosphate transport system regulator, conjectural; Regulatory functions; General.
 
  
 0.452
PAE3068
Phosphoglycolate phosphatase (pgp), conjectural; Energy metabolism; Sugars.
  
  
 0.430
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.