STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1127Conserved hypothetical protein. (306 aa)    
Predicted Functional Partners:
PAE3247
Morphine 6-dehydrogenase, conjectural; Unclassified.
 
 
 0.852
PAE1381
Aldo-keto reductase family protein; Unclassified.
 
 
0.720
PAE0606
Oxidoreductase, conjectural; Unclassified.
 
 
0.708
PAE2929
Aldo-keto reductase, putative; Unclassified.
 
 
0.705
ndk
Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
  
 
 0.644
fni
Conserved protein (possible oxidoreductase); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.608
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.584
PAE1379
long-chain-fatty-acid--CoA ligase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.544
PAE2333
Medium-chain acyl-CoA ligase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.544
PAE2466
long-chain-fatty-acid--CoA ligase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.544
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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