Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE1131Flavoprotein reductase, conjectural; Central intermediary metabolism; Sulfur metabolism. (388 aa)    
Predicted Functional Partners:
PAE1130
Hypothetical protein.
       0.554
PAE1540
Conserved protein (possibly metallo-beta-lactamase superfamily); Unclassified.
   
 0.548
PAE3376
Beta-lactamase-like protein; Cellular processes; Toxin production and resistance.
   
 0.548
PAE3381
Beta-lactamase-like protein; Cellular processes; Toxin production and resistance.
   
 0.548
PAE3498
Hypothetical protein.
   
 0.548
PAE1543
Conserved hypothetical protein.
  
 
 0.523
PAE2095
Hypothetical; Conserved within genome.
  
 
 0.523
PAE2310
Proline dehydrogenase; Amino acid biosynthesis; Serine family.
  
 
 0.523
PAE2703
Conserved hypothetical protein.
  
 
 0.523
PAE2619
Conserved hypothetical protein.
  
    0.514
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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