Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1173Conserved hypothetical protein. (375 aa)    
Predicted Functional Partners:
PAE1175
2-hydroxyacid dehydrogenase; Unclassified; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.714
PAE1176
Hypothetical protein.
       0.677
PAE1171
Conserved hypothetical protein.
       0.565
PAE1177
Hypothetical protein.
       0.550
PAE1049
Hypothetical protein.
 
     0.522
PAE3175
Conserved hypothetical protein.
  
     0.482
PAE3657
Transport and binding proteins; Unknown substrate.
  
     0.475
PAE2546
paREP11.
  
     0.452
PAE0055
Hypothetical protein.
  
     0.449
PAE1168
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Anions.
       0.447
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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