Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1185Galactokinase; Energy metabolism; Sugars. (361 aa)    
Predicted Functional Partners:
PAE1184
Galactose-1-phosphate uridylyltransferase; Energy metabolism; Sugars.
 0.999
PAE1186
Conserved hypothetical protein.
  
    0.838
PAE0870
Conserved NAD/P oxidoreductase; Unclassified.
  
 
 0.823
PAE0318
Hypothetical protein.
 
  
 0.701
PAE3473
Conserved hypothetical protein.
    
   0.676
PAE1736
Beta-glucosidase; Energy metabolism; Sugars; Belongs to the glycosyl hydrolase 1 family.
 
   
 0.645
PAE3437
Glucokinase (ROK family protein), conjectural; Energy metabolism; Sugars.
 
  
 0.598
PAE1968
Alpha-glucosidase; Energy metabolism; Sugars; Belongs to the glycosyl hydrolase 31 family.
 
  
 0.581
PAE3428
Conserved hypothetical protein.
 
     0.545
PAE1610
Glucose-6-phosphate isomerase, conjectural; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
   
 
 0.544
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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