Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1189Acylamino-acid-releasing enzyme, conjectural; Protein fate; Protein modification and repair. (570 aa)    
Predicted Functional Partners:
PAE0264
Signal peptidase; Protein fate; Protein and peptide secretion and trafficking.
  
 
 0.599
PAE1188
Hypothetical protein.
       0.560
PAE1302
Tricorn protease; Degrades oligopeptides; Belongs to the peptidase S41B family.
  
   
 0.539
PAE1525
Glu-tRNA(Gln) amidotransferase subunit A (gatA); Protein synthesis; tRNA aminoacylation.
   
  
 0.485
PAE3237
Beta-lactamase-like protein; Cellular processes; Toxin production and resistance.
  
     0.446
PAE1983
Aerolysin, part 2, authentic frameshift; Protein fate; Degradation of proteins, peptides, and glycopeptides.
  
 
 0.416
PAE0885
Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
  
    0.400
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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