Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1222ABC transporter ATP-binding protein, putative; Transport and binding proteins; Unknown substrate. (356 aa)    
Predicted Functional Partners:
PAE1297
Transport and binding proteins; Amino acids, peptides and amines.
 
     
0.869
PAE3570
Sulfate ABC transporter, permease protein, putative; Transport and binding proteins; Anions.
  
   0.725
PAE3455
Maltose ABC transporter, maltose binding protein; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
  
 0.687
PAE1322
Multiple sugar transport permease; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
   
 0.682
PAE3457
Maltose ABC transporter, permease protein; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
   
 0.664
PAE3456
Maltose ABC transporter, permease protein; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
   
 0.663
PAE1220
acetyl-CoA C-acetyltransferase; Fatty acid and phospholipid metabolism; Degradation.
       0.653
PAE1323
Multiple sugar transport permease; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
   
 0.626
PAE2890
Transport and binding proteins; Amino acids, peptides and amines.
 
 
 
0.610
PAE0686
Multiple sugar transport permease protein; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
   
 0.606
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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