Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1246Manganese ABC transporter ATP-binding protein; Transport and binding proteins; Cations. (242 aa)    
Predicted Functional Partners:
PAE1247
Transport and binding proteins; Cations.
 
 0.999
PAE0564
Conserved hypothetical protein.
  
  
 0.974
PAE2890
Transport and binding proteins; Amino acids, peptides and amines.
  
  
 
0.913
PAE2309
Ferric uptake regulator, putative; Regulatory functions; General.
 
  
 0.788
PAE2022
Conserved (helix-turn-helix protein, copG family); Regulatory functions; General.
     
 0.713
PAE3619
Nitrate ABC transport, ATP-binding protein, putative; Transport and binding proteins; Anions.
 
    0.708
PAE3571
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Anions.
  
     0.693
PAE0731
Transcriptional regulatory protein, conjectural; Regulatory functions; General.
  
  
 0.625
rpl14
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
     0.590
PAE1222
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Unknown substrate.
  
  
 
0.585
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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