Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1288Conserved hypothetical protein. (309 aa)    
Predicted Functional Partners:
PAE1289
Conserved hypothetical protein.
 
 
 0.946
PAE1287
Malate synthase (glcB); Central intermediary metabolism; Other.
  
  
 0.754
PAE1286
Glycolate oxidase subunit glcD; Central intermediary metabolism; Other.
  
  
 0.665
PAE1284
Glycolate oxidase subunit glcE; Central intermediary metabolism; Other.
  
  
 0.632
PAE1282
Glycolate oxidase subunit glcF; Central intermediary metabolism; Other.
       0.505
gap
Glyceraldehyde-3-phosphate dehydrogenase; Energy metabolism; Glycolysis/gluconeogenesis.
   
  
 0.453
PAE1774
Conserved hypothetical protein.
 
  
 0.420
PAE1113
Possible DNA-directed DNA polymerase (B2); DNA metabolism; DNA replication, recombination, and repair.
  
     0.414
PAE1383
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
 
  
 0.413
PAE2566
Siroheme-sulfite reductase gamma subunit homolog; Central intermediary metabolism; Sulfur metabolism.
 
 
 
 0.411
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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