Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE1337Cytochrome C oxidase subunit I /III; Energy metabolism; Electron transport; Belongs to the heme-copper respiratory oxidase family. (800 aa)    
Predicted Functional Partners:
PAE1338
Cytochrome C oxidase subunit II; Energy metabolism; Electron transport.
 
 0.999
PAE1355
Cytochrome C oxidase subunit II; Energy metabolism; Electron transport.
 
 0.998
ctaB1
Cytochrome C oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.997
ctaB2
Cytochrome C oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.993
PAE1350
Cytochrome b/b6; Energy metabolism; Electron transport.
 
 
 0.987
PAE1349
Rieske iron sulfur protein (parR); Energy metabolism; Electron transport.
 
 0.976
PAE1581
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
 
 0.964
PAE1567
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
 
 0.958
PAE3520
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
   
 
 0.957
PAE1357
Cytochrome C oxidase subunit I; Energy metabolism; Electron transport; Belongs to the heme-copper respiratory oxidase family.
 
  
0.949
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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