Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1358senC homolog; Energy metabolism; Electron transport. (207 aa)    
Predicted Functional Partners:
PAE1355
Cytochrome C oxidase subunit II; Energy metabolism; Electron transport.
 
 0.948
PAE1338
Cytochrome C oxidase subunit II; Energy metabolism; Electron transport.
 
 0.903
PAE1357
Cytochrome C oxidase subunit I; Energy metabolism; Electron transport; Belongs to the heme-copper respiratory oxidase family.
 
 
 0.902
PAE1359
Hypothetical protein.
       0.773
PAE1337
Cytochrome C oxidase subunit I /III; Energy metabolism; Electron transport; Belongs to the heme-copper respiratory oxidase family.
 
 
 0.738
PAE1362
nosD homolog; Energy metabolism; Electron transport.
 
     0.726
PAE2366
Glutaredoxin-like protein; Purines, pyrimidines, nucleosides, and nucleotides; 2'-Deoxyribonucleotide metabolism.
  
 
 0.688
PAE2374
Hypothetical protein.
  
 
 0.688
PAE1361
Hypothetical protein.
     
 0.636
PAE1204
Pantothenate metabolism flavoprotein (dfp); DNA metabolism; DNA replication, recombination, and repair.
  
 
 0.626
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.