Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE1381Aldo-keto reductase family protein; Unclassified. (314 aa)    
Predicted Functional Partners:
PAE1379
long-chain-fatty-acid--CoA ligase; Fatty acid and phospholipid metabolism; Degradation.
  
 
 0.767
PAE1127
Conserved hypothetical protein.
 
 
0.690
PAE1383
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
  
  
 0.646
PAE1378
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
  
 
 0.604
PAE2687
Alcohol dehydrogenase (Zinc); Energy metabolism; Fermentation.
  
 
 0.570
PAE1385
Aminopeptidase from family M42; Unclassified.
       0.540
PAE1377
acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
  
 
 0.534
sod
Superoxide dismutase (sod); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.442
PAE1375
Conserved protein associated with acetyl-CoA C-acyltransferase; Fatty acid and phospholipid metabolism; Degradation.
       0.415
PAE3001
Isochorismatase, putative; Biosynthesis of cofactors, prosthetic groups, and carriers; Other.
  
    0.409
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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