close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1472Acetyl/acyl transferase related protein; Fatty acid and phospholipid metabolism; Biosynthesis. (226 aa)    
Predicted Functional Partners:
PAE2053
Pleiotropic regulatory protein, conjectural; Regulatory functions; General; Belongs to the DegT/DnrJ/EryC1 family.
  
 0.928
PAE0870
Conserved NAD/P oxidoreductase; Unclassified.
 
  
 0.762
PAE3281
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.741
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.576
PAE0793
Conserved protein (possible ATP binding); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.570
PAE2970
Conserved hypothetical protein.
 
    0.555
PAE0376
Asparagine synthetase (asnB); Amino acid biosynthesis; Aspartate family.
 
  
 0.551
PAE3030
Oligosaccharyl transferase STT3 homolog; Protein fate; Protein modification and repair.
 
   
 0.537
PAE3488
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
   
 0.533
PAE1922
UDP-glucose 4-epimerase (galE-1); Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.511
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.