Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE1472Acetyl/acyl transferase related protein; Fatty acid and phospholipid metabolism; Biosynthesis. (226 aa)    
Predicted Functional Partners:
PAE2053
Pleiotropic regulatory protein, conjectural; Regulatory functions; General; Belongs to the DegT/DnrJ/EryC1 family.
  
 0.926
PAE0870
Conserved NAD/P oxidoreductase; Unclassified.
 
  
 0.816
PAE3281
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.810
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.649
PAE0793
Conserved protein (possible ATP binding); Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.525
PAE3030
Oligosaccharyl transferase STT3 homolog; Protein fate; Protein modification and repair.
 
   
 0.493
PAE1922
UDP-glucose 4-epimerase (galE-1); Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.491
PAE1051
Cysteine synthase; Amino acid biosynthesis; Serine family.
   
 
 0.483
PAE2970
Conserved hypothetical protein.
 
    0.481
PAE3488
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Cell envelope; Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
   
 0.464
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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