Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAE1503Hypothetical protein. (117 aa)    
Predicted Functional Partners:
PAE2185
3-oxoacyl-[acyl-carrier-protein] synthase; Fatty acid and phospholipid metabolism; Degradation; Belongs to the thiolase-like superfamily. UPF0219 family.
  
 
 0.879
PAE1502
Hypothetical protein.
       0.583
PAE1013
Polyprenyl synthetase; Unclassified; Belongs to the FPP/GGPP synthase family.
  
 
 0.553
PAE3294
Polyprenyl synthetase; Unclassified; Belongs to the FPP/GGPP synthase family.
  
 
 0.553
PAE2979
Methyltransferase; Unclassified.
  
 
 0.525
PAE0696
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
    
 
 0.495
PAE3171
AAA family ATPase, possible cell division control protein cdc48; Cellular processes; Cell division.
    
 
 0.495
PAE2464
ABC transporter ATP-binding component; Transport and binding proteins; Amino acids, peptides and amines.
  
 
 0.473
PAE3547
Heat shock protein, htpX homolog, conjectural; Cellular processes; Adaptations to atypical conditions.
 
 
 0.469
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 
 0.444
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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