STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1584Hypothetical; Conserved within genome. (304 aa)    
Predicted Functional Partners:
PAE2983
Conserved hypothetical protein.
  
  
 0.728
PAE1585
paREP10, authentic frameshift; Hypothetical; Conserved within genome.
       0.584
PAE1583
paREP2a; Hypothetical; Conserved within genome.
       0.548
PAE1589
3-oxoacyl-(acyl carrier protein) reductase; Fatty acid and phospholipid metabolism; Biosynthesis.
  
 
 0.534
PAE1582
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
    0.479
PAE1580
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
    0.478
PAE1581
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
  
    0.478
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
  
 
 0.454
ilvE
Branched-chain amino acid aminotransferase (ilvE); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.444
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.436
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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