Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE15893-oxoacyl-(acyl carrier protein) reductase; Fatty acid and phospholipid metabolism; Biosynthesis. (224 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid.
   
 
 0.845
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
  
 0.805
PAE2904
Exonuclease sbcD, conjectural; DNA metabolism; DNA replication, recombination, and repair.
  
 
 0.707
PAE0692
Hypothetical protein with partial (eukaryotic) protein kinase domain; Unclassified.
  
 0.674
PAE0815
Serine/threonine protein kinase, putative; Regulatory functions; General.
  
 0.674
PAE1350
Cytochrome b/b6; Energy metabolism; Electron transport.
  
 
 0.620
PAE2795
Serine protease; Protein fate; Degradation of proteins, peptides, and glycopeptides.
 
 
 0.595
PAE2926
NADH-ubiquinone oxidoreductase subunit; Energy metabolism; Electron transport.
   
 
 0.571
PAE1650
enoyl-CoA hydratase, probable; Fatty acid and phospholipid metabolism; Degradation.
  
 0.568
PAE2479
enoyl-CoA hydratase; Fatty acid and phospholipid metabolism; Degradation.
  
 0.568
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.