node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PAE0768 | glyA | PAE0768 | PAE0798 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.540 |
PAE0768 | guaA | PAE0768 | PAE3369 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.816 |
PAE0768 | pyrB | PAE0768 | PAE0770 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | Aspartate carbamoyltransferase catalytic subunit (pyrB); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | 0.995 |
PAE0768 | pyrH | PAE0768 | PAE3159 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP. | 0.953 |
PAE0768 | surE1 | PAE0768 | PAE2908 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | surE stationary-phase survival protein homolog; Nucleotidase that shows the greatest phosphatase activity on purine (deoxy)nucleoside 5'-monophosphates, particularly the substrates 5'-GMP, 5'-AMP and 2'-deoxy-5'-AMP; Belongs to the SurE nucleotidase family. | 0.924 |
PAE0768 | surE2 | PAE0768 | PAE3523 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | surE stationary-phase survival protein homolog; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.933 |
PAE0768 | upp | PAE0768 | PAE1598 | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.959 |
PAE1597 | glyA | PAE1597 | PAE0798 | Aminopeptidase; Unclassified. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.871 |
PAE1597 | upp | PAE1597 | PAE1598 | Aminopeptidase; Unclassified. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.821 |
PAE3111 | surE1 | PAE3111 | PAE2908 | Uridine phosphorylase; Purines, pyrimidines, nucleosides, and nucleotides; Salvage of nucleosides and nucleotides. | surE stationary-phase survival protein homolog; Nucleotidase that shows the greatest phosphatase activity on purine (deoxy)nucleoside 5'-monophosphates, particularly the substrates 5'-GMP, 5'-AMP and 2'-deoxy-5'-AMP; Belongs to the SurE nucleotidase family. | 0.906 |
PAE3111 | surE2 | PAE3111 | PAE3523 | Uridine phosphorylase; Purines, pyrimidines, nucleosides, and nucleotides; Salvage of nucleosides and nucleotides. | surE stationary-phase survival protein homolog; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.906 |
PAE3111 | upp | PAE3111 | PAE1598 | Uridine phosphorylase; Purines, pyrimidines, nucleosides, and nucleotides; Salvage of nucleosides and nucleotides. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.920 |
glyA | PAE0768 | PAE0798 | PAE0768 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | 0.540 |
glyA | PAE1597 | PAE0798 | PAE1597 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminopeptidase; Unclassified. | 0.871 |
glyA | guaA | PAE0798 | PAE3369 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.854 |
glyA | pyrB | PAE0798 | PAE0770 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate carbamoyltransferase catalytic subunit (pyrB); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | 0.506 |
glyA | pyrH | PAE0798 | PAE3159 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP. | 0.493 |
glyA | rps2 | PAE0798 | PAE0817 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the universal ribosomal protein uS2 family. | 0.502 |
glyA | upp | PAE0798 | PAE1598 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.914 |
guaA | PAE0768 | PAE3369 | PAE0768 | GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Orotidine-5'-monophosphate decarboxylase (pyrF); Purines, pyrimidines, nucleosides, and nucleotides; Pyrimidine ribonucleotide biosynthesis. | 0.816 |