STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1629Adenylate kinase, conjectural; Purines, pyrimidines, nucleosides, and nucleotides; Nucleotide and nucleoside interconversions; Belongs to the UPF0200 family. (174 aa)    
Predicted Functional Partners:
PAE1627
Hypothetical protein.
 
     0.852
trm1
N2,N2-dimethylguonasine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.825
PAE1632
Conserved hypothetical protein; Belongs to the UPF0201 family.
 
    0.750
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.726
PAE1599
Hypothetical protein.
  
  
 0.720
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.648
PAE0880
DNA-(apurinic or apyrimidinic site) lyase (endonuclease III, PaNth); DNA metabolism; DNA replication, recombination, and repair.
  
    0.646
gap
Glyceraldehyde-3-phosphate dehydrogenase; Energy metabolism; Glycolysis/gluconeogenesis.
 
   
 0.609
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.605
PAE3406
Conserved hypothetical protein.
 
     0.602
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.