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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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[Homology]
Score
gapGlyceraldehyde-3-phosphate dehydrogenase; Energy metabolism; Glycolysis/gluconeogenesis. (344 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
pgk
Phosphoglycerate kinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the phosphoglycerate kinase family.
 
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.990
PAE1610
Glucose-6-phosphate isomerase, conjectural; Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
 
 0.988
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
 
 
 0.972
PAE1029
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
    
 0.950
pyk
Pyruvate kinase; Energy metabolism; Glycolysis/gluconeogenesis; Belongs to the pyruvate kinase family.
 
 
 0.940
PAE1738
Conserved hypothetical protein.
  
  
 0.940
PAE1929
Transketolase (N terminal section); Energy metabolism; Pentose phosphate pathway.
    
 0.929
rps6e
Protein synthesis; Ribosomal proteins: synthesis and modification; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.922
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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