Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1759Molybdopterin-guanine dinucleotide biosynthesis protein B, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin. (149 aa)    
Predicted Functional Partners:
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
 
 0.953
PAE3453
Molybdopterin-guanine dinucleotide biosynthesis protein A; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
 
 0.855
PAE1760
Conserved hypothetical protein.
       0.792
PAE1761
Myo-inositol-1-phosphate synthase, conjectural; Fatty acid and phospholipid metabolism; Other.
       0.792
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
    0.683
PAE3048
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
 
 0.662
PAE1762
Iron-sulfur binding reductase, probable; Energy metabolism; Electron transport.
       0.623
PAE3466
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
 
 0.610
PAE3465
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
 
 0.595
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
   
 0.545
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.