STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1785Conserved hypothetical protein. (227 aa)    
Predicted Functional Partners:
PAE1784
Conserved hypothetical protein.
  
    0.808
PAE1783
Hypothetical protein.
       0.554
PAE3526
Hypothetical protein.
 
   
 0.504
PAE1226
DNA endonuclease, conjectural; DNA metabolism; DNA replication, recombination, and repair.
 
  
 0.474
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.455
PAE0055
Hypothetical protein.
 
     0.439
PAE2795
Serine protease; Protein fate; Degradation of proteins, peptides, and glycopeptides.
  
 
 0.432
PAE2839
Molybdopterin oxidoreductase, molybdopterin binding subunit part 2, authentic frameshift; Energy metabolism; Electron transport.
 
     0.417
PAE1683
Hypothetical protein.
 
 
 
 0.416
rpl22
Ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
       0.413
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.