Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1785Conserved hypothetical protein. (227 aa)    
Predicted Functional Partners:
PAE1784
Conserved hypothetical protein.
  
    0.808
PAE1783
Hypothetical protein.
       0.554
PAE2095
Hypothetical; Conserved within genome.
 
 
 0.553
PAE2703
Conserved hypothetical protein.
 
 
 0.553
PAE1543
Conserved hypothetical protein.
 
 
 0.544
PAE3301
mutT/nudix family protein; DNA metabolism; DNA replication, recombination, and repair.
 
 
 0.520
fni
Conserved protein (possible oxidoreductase); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
  0.508
PAE2795
Serine protease; Protein fate; Degradation of proteins, peptides, and glycopeptides.
  
 
  0.507
PAE1378
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
   
 0.500
PAE2070
acyl-CoA dehydrogenase; Fatty acid and phospholipid metabolism; Degradation.
   
 0.500
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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