STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1807Hypothetical; Conserved within genome. (93 aa)    
Predicted Functional Partners:
PAE2480
Aldehyde dehydrogenase; Unclassified.
  
 
 0.725
PAE1808
ABC transporter, putative; Transport and binding proteins; Unknown substrate.
  
    0.674
PAE1809a
paREP2a; Hypothetical; Conserved within genome.
       0.538
guaA
GMP synthetase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.514
PAE3321
Aminotransferase (class 5); Unclassified.
  
 
 0.498
PAE3447
Aminotransferase, class-V; Unclassified.
  
 
 0.498
ilvE
Branched-chain amino acid aminotransferase (ilvE); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.477
PAE1810
paREP2a; Hypothetical; Conserved within genome.
       0.438
PAE2075
Nitrilase, conjectural; Unclassified.
  
  
 0.412
PAE2688
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, conjectural; Central intermediary metabolism; Other.
  
 
 0.412
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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