Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1884Phosphate permease, conjectural; Transport and binding proteins; Anions. (299 aa)    
Predicted Functional Partners:
PAE3187
Conserved hypothetical protein.
  
  
 0.924
lysS
lysyl-tRNA synthetase; Protein synthesis; tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.599
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
  
    0.580
PAE2609
Sulfate adenylyltransferase; Central intermediary metabolism; Sulfur metabolism.
 
  
 0.559
PAE2575
Phosphoadenosine phosphosulfate reductase (PAPS reductase); Central intermediary metabolism; Sulfur metabolism.
 
  
 0.525
PAE2700
Hypothetical protein.
     
 0.516
PAE3063
Conserved hypothetical protein.
  
 
 0.510
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.483
PAE1395
Phosphate ABC transporter, permease protein; Transport and binding proteins; Anions.
     
 0.483
PAE1396
Phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
     
 0.483
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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