Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE1920phoH like protein; Regulatory functions; General. (371 aa)    
Predicted Functional Partners:
PAE1921
Alcohol dehydrogenase (Zinc); Energy metabolism; Fermentation.
       0.698
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
       0.660
PAE3175
Conserved hypothetical protein.
  
     0.636
PAE1918
mutT/nudix family protein; DNA metabolism; DNA replication, recombination, and repair.
       0.574
fau-1
Conserved hypothetical protein; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
 
    0.558
PAE1300
Transport and binding proteins; Amino acids, peptides and amines.
 
     0.532
PAE1372
Conserved hypothetical protein.
  
    0.493
PAE1013
Polyprenyl synthetase; Unclassified; Belongs to the FPP/GGPP synthase family.
 
    0.427
PAE1173
Conserved hypothetical protein.
  
     0.425
PAE0743
RNA binding protein (fmu, PCNA P120 homolog), probable; Protein fate; Protein modification and repair.
 
     0.416
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.