STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1964Aspartate aminotransferase (aspC), conjectural; Amino acid biosynthesis; Aspartate family. (330 aa)    
Predicted Functional Partners:
PAE0958
Histidinol-phosphate aminotransferase (hisC); Amino acid biosynthesis; Histidine family.
 
 
 0.941
PAE1941
Chorismate mutase, conjectural; Amino acid biosynthesis; Aromatic amino acid family.
    
 0.941
argG
Argininosuccinate synthase (argG); Amino acid biosynthesis; Glutamate family; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.941
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.939
PAE1051
Cysteine synthase; Amino acid biosynthesis; Serine family.
 
 0.938
PAE3227
Glutamate synthase small subunit gltD; Amino acid biosynthesis; Glutamate family.
 
 
 0.938
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.933
PAE0918
Histidinol-phosphate aminotransferase (hisC); Amino acid biosynthesis; Histidine family.
 
 
0.929
PAE0893
Chorismate mutase/prephenate dehydratase (P-protein); Amino acid biosynthesis; Aromatic amino acid family.
  
 
 0.924
PAE1996
Amino acid biosynthesis; Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.923
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.