Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE1968Alpha-glucosidase; Energy metabolism; Sugars; Belongs to the glycosyl hydrolase 31 family. (684 aa)    
Predicted Functional Partners:
PAE1736
Beta-glucosidase; Energy metabolism; Sugars; Belongs to the glycosyl hydrolase 1 family.
 
 0.968
PAE3428
Conserved hypothetical protein.
 
  
 0.957
PAE1209
4-alpha-glucanotransferase (malQ); Energy metabolism; Biosynthesis and degradation of polysaccharides.
    
 0.926
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
   0.785
PAE2366
Glutaredoxin-like protein; Purines, pyrimidines, nucleosides, and nucleotides; 2'-Deoxyribonucleotide metabolism.
  
 
 0.770
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
   
   0.746
PAE1969
Conserved hypothetical protein.
       0.746
PAE3333
Conserved hypothetical protein.
    
 0.743
PAE2374
Hypothetical protein.
   
 
 0.737
PAE1499
Aconitate hydratase; Energy metabolism; TCA cycle.
   
 
 0.727
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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