STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE1982Aerolysin, part 1, authentic frameshift; Protein fate; Degradation of proteins, peptides, and glycopeptides. (174 aa)    
Predicted Functional Partners:
PAE1983
Aerolysin, part 2, authentic frameshift; Protein fate; Degradation of proteins, peptides, and glycopeptides.
     0.958
leuC
3-isopropylmalate dehydratase large subunit (leuC); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.688
rpoL
DNA-directed RNA polymerase subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
       0.639
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
       0.639
PAE1981
Hypothetical protein.
       0.639
PAE1049
Hypothetical protein.
  
  
 0.579
PAE1861
Hypothetical protein with 4 ankyrin repeats; Unclassified.
 
 
 0.522
PAE2662
Formate dehydrogenase alpha subunit; Energy metabolism; Electron transport.
 
     0.501
PAE2546
paREP11.
  
    0.477
PAE3117
Small heat shock protein, hsp20 homolog, conjectural; Cellular processes; Adaptations to atypical conditions; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.442
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.